Tawny Chandler
RESEARCH ASSOCIATE
Tawny is a Research Associate in the Caddy lay with a special interest in the immuno-physiology of the maternal dyad. Tawny began her research career in animal science, as she was born and raised on a dairy farm in Wisconsin. She obtained specialized training in nutritional physiology at the University of Wisconsin-Madison where she received her MS and PhD. She came to Cornell for her first postdoc in nutritional immunology where she developed an expertise in basic and applied immunology. She was awarded a USDA-NIFA AFRI Postdoctoral Fellowship to study the ability of nutrients to modulate innate immune responses in the bovine. She further expanded her training to neonates and developed novel insight on the maternally derived factors that affect the immunity of neonatal calves.
After her first post-doc, Tawny became a part of her own maternal dyad and wanted to expand her expertise in maternal immunity to humans and other species. She joined the Caddy Lab in April 2023 and developed an expertise in breeding and infecting neonatal mice with a range of pathogens including LCMV, rotavirus, and influenza. She has begun working with large genomic datasets and has expertise working with single cell RNA-seq data. Her current projects included investigating the mechanisms of maternal antibody interference in a neonatal model of oral rotavirus vaccination and the protective functions of maternal antibodies in neonatal infections.
Outside of the lab… she enjoys spending time with her family, including hiking with Nora and Barry, and baking up a storm.
References
Publications
Chandler TL, Woodyear S, Chen V, Lonergan TM, Baker N, Harcourt K, Clare S, Ahmed F, Caddy SL. Mechanisms of maternal antibody interference with rotavirus vaccination. EMBO J. 2025 Oct 14. doi: 10.1038/s44318-025-00582-2. Epub ahead of print. PMID: 41087582.
Woodyear S, Chandler TL, Kawagishi T, Lonergan TM, Patel VA, Williams CA, Permar SR, Ding S, Caddy SL. Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice. Viruses. 2024 Jul 16;16(7):1145. doi: 10.3390/v16071145. PMID: 39066309; PMCID: PMC11281508
Chandler TL, Yang A, Otero C, Permar S and Caddy S. Protective mechanisms of non-neutralizing anti-viral antibodies. PLoS Pathog. 2023 Oct 5;19(10):e1011670. PMC10553219.
A complete list of published work is available in MyBibliography.
Awards
2025 ASV Postdoc travel grant
Conferences - Poster
T.L. Chandler, S.A.K. Woodyear, V. Patel, T. Lonergan, S. Caddy. 2024. Maternal anti-nucleoprotein antibody protects against lethal LCMV infection. American Society for Virology Annual Meeting, Columbus, Ohio, US.
Conferences - Oral
T.L. Chandler, S. Woodyear, T. Lonergan, N. Baker, V. Chen, S. Clare, K. Holt, S. L. Caddy. 2025. Mechanisms of maternal antibody interference to oral rotavirus vaccination. 15th International dsRNA Virus Symposium, November 7, 2025, Porto, Portugal.
T.L. Chandler, S. Woodyear, T. Lonergan, N. Baker, V. Chen, S. Clare, K. Holt, S. L. Caddy. 2025. Mechanisms of maternal antibody interference to oral rotavirus vaccination. American Society for Virology Annual Meeting, Montreal, Canada.